This Primary Care Briefing has been produced to inform healthcare professionals in primary care of the new daily. excluded if they had not responded to PDE5 inhibitors in the past. Once-daily tadalafil was not compared with on-. Comparison of phosphodiesterase type 5 (PDE5) inhibitors. Int J Clin Pract 2006; 60(8):967-975.
PDE-5 inhibitor for erectile dysfunction In erectile dysfunction, too little blood gets into the penis, so that an erection is difficult or completely impossible, even with sexual arousal.PDE-5 inhibitors promote blood circulation so that an erection becomes possible again.